4a4m

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'''Unreleased structure'''
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[[Image:4a4m.jpg|left|200px]]
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The entry 4a4m is ON HOLD
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{{STRUCTURE_4a4m| PDB=4a4m | SCENE= }}
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Authors: Deupi, X., Edwards, P., Singhal, A., Nickle, B., Oprian, D.D., Schertler, G.F.X., Standfuss, J.
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===Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)===
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Description: Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)
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{{ABSTRACT_PUBMED_22198838}}
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==About this Structure==
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[[4a4m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4M OCA].
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==Reference==
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<ref group="xtra">PMID:022198838</ref><ref group="xtra">PMID:017825322</ref><ref group="xtra">PMID:021389983</ref><references group="xtra"/>
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[[Category: Bos taurus]]
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[[Category: Deupi, X.]]
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[[Category: Edwards, P.]]
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[[Category: Nickle, B.]]
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[[Category: Oprian, D D.]]
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[[Category: Schertler, G F.X.]]
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[[Category: Singhal, A.]]
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[[Category: Standfuss, J.]]
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[[Category: G-protein]]
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[[Category: G-protein-coupled receptor]]
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[[Category: Metarhodopsin-ii]]
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[[Category: Signal tansduction]]
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[[Category: Signaling protein]]
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[[Category: Visual system]]

Revision as of 06:28, 25 January 2012

Image:4a4m.jpg

Template:STRUCTURE 4a4m

Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)

Template:ABSTRACT PUBMED 22198838

About this Structure

4a4m is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J. Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II. Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):119-24. Epub 2011 Dec 23. PMID:22198838 doi:10.1073/pnas.1114089108
  • Standfuss J, Xie G, Edwards PC, Burghammer M, Oprian DD, Schertler GF. Crystal structure of a thermally stable rhodopsin mutant. J Mol Biol. 2007 Oct 5;372(5):1179-88. Epub 2007 Mar 12. PMID:17825322 doi:10.1016/j.jmb.2007.03.007
  • Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, Schertler GF. The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature. 2011 Mar 31;471(7340):656-60. Epub 2011 Mar 9. PMID:21389983 doi:10.1038/nature09795

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