3uuo

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'''Unreleased structure'''
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[[Image:3uuo.jpg|left|200px]]
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The entry 3uuo is ON HOLD until Paper Publication
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{{STRUCTURE_3uuo| PDB=3uuo | SCENE= }}
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Authors: Ho, G.D., Yang, S., Smotryski, J., Bercovici, A., Nechuta, T., Smith, E.M., McElroy, W., Tan, Z., Tulshian, D., Mckittrick, B., Greenlee, W.J., Hruza, A., Xiao, L., Rindgen, D., Guzzi, M., Zhang, X., Bleickardt, C., Mullins, D., Hodgson, R.
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===The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10 inhibitors for the treatment of Schizophrenia===
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Description: The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10 inhibitors for the treatment of Schizophrenia
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The line below this paragraph, {{ABSTRACT_PUBMED_22222034}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 22222034 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22222034}}
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==About this Structure==
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[[3uuo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UUO OCA].
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==Reference==
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<ref group="xtra">PMID:022222034</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Bercovici, A.]]
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[[Category: Bleickardt, C.]]
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[[Category: Greenlee, W J.]]
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[[Category: Guzzi, M.]]
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[[Category: Ho, G D.]]
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[[Category: Hodgson, R.]]
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[[Category: Hruza, A.]]
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[[Category: McElroy, W.]]
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[[Category: Mckittrick, B.]]
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[[Category: Mullins, D.]]
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[[Category: Nechuta, T.]]
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[[Category: Rindgen, D.]]
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[[Category: Smith, E M.]]
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[[Category: Smotryski, J.]]
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[[Category: Tan, Z.]]
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[[Category: Tulshian, D.]]
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[[Category: Xiao, L.]]
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[[Category: Yang, S.]]
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[[Category: Zhang, X.]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Inhibitor complex]]
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[[Category: Mg binding]]
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[[Category: Zn binding]]

Revision as of 06:32, 25 January 2012

Image:3uuo.jpg

Template:STRUCTURE 3uuo

The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10 inhibitors for the treatment of Schizophrenia

Template:ABSTRACT PUBMED 22222034

About this Structure

3uuo is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ho GD, Yang SW, Smotryski J, Bercovici A, Nechuta T, Smith EM, McElroy W, Tan Z, Tulshian D, McKittrick B, Greenlee WJ, Hruza A, Xiao L, Rindgen D, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1019-22. Epub 2011 Dec 9. PMID:22222034 doi:10.1016/j.bmcl.2011.11.127

Proteopedia Page Contributors and Editors (what is this?)

OCA

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