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Focal adhesion kinase

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(New page: {{STRUCTURE_2ijm| PDB=2ijm | SIZE=400| SCENE= |right|CAPTION=Focal adhesion kinase 1 kinase domain complex with ADP and ATP, 2ijm }} {{TOC limit|limit=2}} == 3D Structures of focal...)
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Revision as of 10:12, 25 January 2012

Template:STRUCTURE 2ijm

Contents

3D Structures of focal adhesion kinase

Focal adhesion kinase 1 (FAK1)

FAK1 targeting domain

1k04, 1k05 – hFAK1 targeting domain – human
1ow6, 1ow7 - hFAK1 targeting domain + paxillin LD4 motif
1ow8 - hFAK1 targeting domain + paxillin LD2 motif
3b71 - hFAK1 targeting domain + ADP + ATP
1ktm, 1qvx, 1pv3 - cFAK1 targeting domain – chicken – NMR

FAK1 kinase domain

1mp8 - hFAK1 kinase domain
2etm, 3bz3 - hFAK1 kinase domain + pyrimidine derivative
2ijm - hFAK1 kinase domain + ADP + ATP
2j0l - cFAK1 kinase domain phosphorylated
2jkk, 2jkm, 2jko, 2jkq - cFAK1 kinase domain + pyrimidine derivative

FAK1 FERM domain

2j0j, 2j0k, 2j0m - cFAK1 kinase + FERM domains
2aeh, 2al6 - cFAK1 FERM domain

Focal adhesion kinase 2 (FAK2)

3cc6, 3fzo – hFAK2 kinase domain
3fzp - hFAK2 kinase domain + ATPγS
3fzr, 3fzt, 3h3c, 3et7 – hFAK2 kinase domain + pyrimidine derivative
3fzs – hFAK2 kinase domain + naphthaline derivative

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Michal Harel, Alexander Berchansky

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