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2x9d

From Proteopedia

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{{STRUCTURE_2x9d| PDB=2x9d | SCENE= }}
{{STRUCTURE_2x9d| PDB=2x9d | SCENE= }}
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===TET REPRESSOR (CLASS D) IN COMPLEX WITH ISO-7 CHLORTETRACYCLINE===
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===Tet repressor (class D) in complex with iso-7-chlortetracycline===
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(as it appears on PubMed at http://www.pubmed.gov), where 8153629 is the PubMed ID number.
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(as it appears on PubMed at http://www.pubmed.gov), where 21699184 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8153629}}
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{{ABSTRACT_PUBMED_21699184}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:8153629</ref><references group="xtra"/>
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<ref group="xtra">PMID:021699184</ref><ref group="xtra">PMID:008153629</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Hinrichs, W.]]
[[Category: Hinrichs, W.]]
[[Category: Volkers, G.]]
[[Category: Volkers, G.]]
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[[Category: Antibiotic resistance]]
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[[Category: Dna-binding protein]]
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[[Category: Gene regulation]]
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[[Category: Hth-motif]]
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[[Category: Transcription]]

Revision as of 06:20, 1 February 2012

Image:2x9d.png

Template:STRUCTURE 2x9d

Tet repressor (class D) in complex with iso-7-chlortetracycline

Template:ABSTRACT PUBMED 21699184

About this Structure

2x9d is a 1 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1du7. Full crystallographic information is available from OCA.

Reference

  • Volkers G, Petruschka L, Hinrichs W. Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. J Med Chem. 2011 Jul 28;54(14):5108-15. Epub 2011 Jul 1. PMID:21699184 doi:10.1021/jm200332e
  • Hinrichs W, Kisker C, Duvel M, Muller A, Tovar K, Hillen W, Saenger W. Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance. Science. 1994 Apr 15;264(5157):418-20. PMID:8153629

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OCA

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