3e64

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Template:STRUCTURE 3e64

Fragment based discovery of JAK-2 inhibitors

Template:ABSTRACT PUBMED 19019674

About this Structure

3e64 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Antonysamy S, Hirst G, Park F, Sprengeler P, Stappenbeck F, Steensma R, Wilson M, Wong M. Fragment-based discovery of JAK-2 inhibitors. Bioorg Med Chem Lett. 2009 Jan 1;19(1):279-82. Epub 2008 Aug 22. PMID:19019674 doi:10.1016/j.bmcl.2008.08.064

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