4a6l

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Revision as of 07:33, 1 February 2012

Image:4a6l.png

Template:STRUCTURE 4a6l

beta-tryptase inhibitor

Template:ABSTRACT PUBMED 22192588

About this Structure

4a6l is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liang G, Aldous S, Merriman G, Levell J, Pribish J, Cairns J, Chen X, Maignan S, Mathieu M, Tsay J, Sides K, Rebello S, Whitely B, Morize I, Pauls HW. Structure-based library design and the discovery of a potent and selective mast cell beta-tryptase inhibitor as an oral therapeutic agent. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1049-54. Epub 2011 Dec 7. PMID:22192588 doi:10.1016/j.bmcl.2011.11.119

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OCA

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