4dfu

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Revision as of 07:02, 1 February 2012 (edit) OCA (Talk | contribs) m (Protected "4dfu" [edit=sysop:move=sysop]) ← Previous diff		Revision as of 06:25, 8 February 2012 (edit) (undo) OCA (Talk | contribs) Next diff →
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-	'''Unreleased structure'''	+	[[Image:4dfu.jpg|left|200px]]
-	The entry 4dfu is ON HOLD	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4dfu", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4dfu| PDB=4dfu | SCENE= }}
-	Authors: Stogios, P.J., Dong, A., Evdokimova, E., Egorova, E., Di Leo, R., Li, H., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)	+	===Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin===
-	Description: Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22195561}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22195561 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22195561}}
		+
		+	==About this Structure==
		+	[[4dfu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_casseliflavus Enterococcus casseliflavus] and [http://en.wikipedia.org/wiki/Streptomyces_kanamyceticus Streptomyces kanamyceticus]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3r82 3r82]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022195561</ref><references group="xtra"/>
		+	[[Category: Enterococcus casseliflavus]]
		+	[[Category: Streptomyces kanamyceticus]]
		+	[[Category: Anderson, W F.]]
		+	[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
		+	[[Category: Dong, A.]]
		+	[[Category: Egorova, E.]]
		+	[[Category: Evdokimova, E.]]
		+	[[Category: Leo, R Di.]]
		+	[[Category: Li, H.]]
		+	[[Category: Minasov, G.]]
		+	[[Category: Savchenko, A.]]
		+	[[Category: Stogios, P J.]]
		+	[[Category: Aminoglycoside phosphotransferase]]
		+	[[Category: Aminoglycoside]]
		+	[[Category: Antibotic]]
		+	[[Category: Center for structural genomics of infectious disease]]
		+	[[Category: Csgid]]
		+	[[Category: Eukaryotic protein kinase-like fold]]
		+	[[Category: Flavanoid]]
		+	[[Category: Intracellular]]
		+	[[Category: Kanamycin]]
		+	[[Category: Kinase]]
		+	[[Category: Quercetin]]
		+	[[Category: Structural genomic]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase-antibiotic-inhibitor complex]]
		+	[[Category: Transferase-antibotic-inhibitor complex]]

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Revision as of 06:25, 8 February 2012

Template:STRUCTURE 4dfu

Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin

Template:ABSTRACT PUBMED 22195561

About this Structure

4dfu is a 2 chain structure with sequence from Enterococcus casseliflavus and Streptomyces kanamyceticus. This structure supersedes the now removed PDB entries and 3r82. Full crystallographic information is available from OCA.

Reference

• Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. A small molecule discrimination map of the antibiotic resistance kinome. Chem Biol. 2011 Dec 23;18(12):1591-601. PMID:22195561 doi:10.1016/j.chembiol.2011.10.018