3u4s
From Proteopedia
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| - | + | [[Image:3u4s.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3u4s", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
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| + | {{STRUCTURE_3u4s| PDB=3u4s | SCENE= }} | ||
| - | + | ===Histone Lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to N-oxalyl-D-cysteine=== | |
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22241642}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22241642 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22241642}} | ||
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| + | ==About this Structure== | ||
| + | [[3u4s]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U4S OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022241642</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Ma, J.]] | ||
| + | [[Category: McDonough, M A.]] | ||
| + | [[Category: Schofield, C J.]] | ||
| + | [[Category: Demethylase]] | ||
| + | [[Category: Double-stranded beta-helix]] | ||
| + | [[Category: Histone 3 tail]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase substrate complex]] | ||
Revision as of 06:26, 8 February 2012
Histone Lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to N-oxalyl-D-cysteine
Template:ABSTRACT PUBMED 22241642
About this Structure
3u4s is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Woon EC, Tumber A, Kawamura A, Hillringhaus L, Ge W, Rose NR, Ma JH, Chan MC, Walport LJ, Che KH, Ng SS, Marsden BD, Oppermann U, McDonough MA, Schofield CJ. Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases. Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1631-4. doi:, 10.1002/anie.201107833. Epub 2012 Jan 12. PMID:22241642 doi:10.1002/anie.201107833
