2onh
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2ONH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mentha_spicata Mentha spicata] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=F3P:'>F3P</scene> and <scene name='pdbligand=BTB:'>BTB</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONH OCA]. | + | 2ONH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mentha_spicata Mentha spicata] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=F3P:'>F3P</scene> and <scene name='pdbligand=BTB:'>BTB</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Mn+Binding+Site+For+Residue+A+601'>AC1</scene>, <scene name='pdbsite=AC2:Mn+Binding+Site+For+Residue+A+602'>AC2</scene>, <scene name='pdbsite=AC3:Mn+Binding+Site+For+Residue+A+603'>AC3</scene>, <scene name='pdbsite=AC4:Mn+Binding+Site+For+Residue+B+1601'>AC4</scene>, <scene name='pdbsite=AC5:Mn+Binding+Site+For+Residue+B+1602'>AC5</scene>, <scene name='pdbsite=AC6:Mn+Binding+Site+For+Residue+B+1603'>AC6</scene>, <scene name='pdbsite=AC7:F3p+Binding+Site+For+Residue+A+600'>AC7</scene>, <scene name='pdbsite=AC8:Btb+Binding+Site+For+Residue+A+604'>AC8</scene> and <scene name='pdbsite=AC9:F3p+Binding+Site+For+Residue+B+1600'>AC9</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONH OCA]. |
==Reference== | ==Reference== | ||
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[[Category: geranyl diphosphate]] | [[Category: geranyl diphosphate]] | ||
[[Category: linalyl diphosphate]] | [[Category: linalyl diphosphate]] | ||
| + | [[Category: lyase]] | ||
[[Category: monoterpene cyclase]] | [[Category: monoterpene cyclase]] | ||
[[Category: monoterpene synthase]] | [[Category: monoterpene synthase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 6 | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 6 17:28:36 2008'' |
Revision as of 15:28, 6 February 2008
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Crystal Structure of of limonene synthase with 2-fluorolinalyl diphosphate(FLPP)
Overview
The crystal structure of (4S)-limonene synthase from Mentha spic ata, a, metal ion-dependent monoterpene cyclase that catalyzes the coupled, isomerization and cyclization of geranyl diphosphate, is reported at, 2.7-A; resolution in two forms liganded to the substrate and intermediate, analogs, 2-fluorogeranyl diphosphate and 2-fluorolinalyl diphosphate, respectively. The implications of these findings are described for domain, interactions in the homodimer and for changes in diphosphate-metal ion, coordination and substrate binding conformation in the course of the, multistep reaction.
About this Structure
2ONH is a Single protein structure of sequence from Mentha spicata with , and as ligands. Known structural/functional Sites: , , , , , , , and . Full crystallographic information is available from OCA.
Reference
Structure of limonene synthase, a simple model for terpenoid cyclase catalysis., Hyatt DC, Youn B, Zhao Y, Santhamma B, Coates RM, Croteau RB, Kang C, Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5360-5. Epub 2007 Mar 19. PMID:17372193
Page seeded by OCA on Wed Feb 6 17:28:36 2008
