4agw

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m (Protected "4agw" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4agw.jpg|left|200px]]
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The entry 4agw is ON HOLD
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{{STRUCTURE_4agw| PDB=4agw | SCENE= }}
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Authors: Weisberg, E., Choi, H.G., Seeliger, M., Gray, N., Griffin, J.D.
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===Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases===
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Description: Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases
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{{ABSTRACT_PUBMED_20299508}}
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==About this Structure==
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[[4agw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGW OCA].
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==Reference==
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<ref group="xtra">PMID:020299508</ref><references group="xtra"/>
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[[Category: Gallus gallus]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Choi, H G.]]
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[[Category: Gray, N.]]
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[[Category: Griffin, J D.]]
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[[Category: Seeliger, M.]]
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[[Category: Weisberg, E.]]
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[[Category: Atp-binding]]
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[[Category: Lipoprotein]]
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[[Category: Myristate]]
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[[Category: Phosphoprotein]]
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[[Category: Sh2 domain]]
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[[Category: Sh3 domain]]
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[[Category: Transferase]]

Revision as of 06:41, 15 February 2012

Image:4agw.jpg

Template:STRUCTURE 4agw

Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases

Template:ABSTRACT PUBMED 20299508

About this Structure

4agw is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Weisberg E, Choi HG, Ray A, Barrett R, Zhang J, Sim T, Zhou W, Seeliger M, Cameron M, Azam M, Fletcher JA, Debiec-Rychter M, Mayeda M, Moreno D, Kung AL, Janne PA, Khosravi-Far R, Melo JV, Manley PW, Adamia S, Wu C, Gray N, Griffin JD. Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants. Blood. 2010 May 27;115(21):4206-16. Epub 2010 Mar 18. PMID:20299508 doi:10.1182/blood-2009-11-251751

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OCA

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