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Fasciculin
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{{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} | {{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} | ||
| - | [[Fasciculin|Fasciculins]] (FASs) are toxins produced by the snake green mamba. FASI and FASII are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]). | + | [[Fasciculin|Fasciculins]] (FASs) are toxins produced by the snake green mamba. FASI and FASII are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]). For toxins in Proteopedia see [[Toxins]]. |
Revision as of 11:51, 19 February 2012
Fasciculins (FASs) are toxins produced by the snake green mamba. FASI and FASII are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, i.e. the crystal structure of Fasciculin 1 (1fas). For toxins in Proteopedia see Toxins.
3D Structures of Fasciculin
Fasciculin
FAS+ AChE
2x8b, 1b41 – FASII+hAChE – human
1f8u - FASII+hAChE (mutant)
1ku6, 1mah - FASII+mAChE – mouse
1fss - FASII+AChE – Torpedo californica
