This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ix0
From Proteopedia
(New page: 200px<br /> <applet load="2ix0" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ix0, resolution 2.44Å" /> '''RNASE II'''<br /> ...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2IX0 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with MG, CA and C5P as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.13.1 3.1.13.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IX0 OCA]]. | + | 2IX0 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with MG, CA and C5P as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Exoribonuclease_II Exoribonuclease II]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.13.1 3.1.13.1]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IX0 OCA]]. |
==Reference== | ==Reference== | ||
Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex., Frazao C, McVey CE, Amblar M, Barbas A, Vonrhein C, Arraiano CM, Carrondo MA, Nature. 2006 Sep 7;443(7107):110-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16957732 16957732] | Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex., Frazao C, McVey CE, Amblar M, Barbas A, Vonrhein C, Arraiano CM, Carrondo MA, Nature. 2006 Sep 7;443(7107):110-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16957732 16957732] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| + | [[Category: Exoribonuclease II]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Amblar, M.]] | [[Category: Amblar, M.]] | ||
| Line 34: | Line 35: | ||
[[Category: s1]] | [[Category: s1]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:56:51 2007'' |
Revision as of 10:52, 30 October 2007
|
RNASE II
Overview
RNA degradation is a determining factor in the control of gene expression., The maturation, turnover and quality control of RNA is performed by many, different classes of ribonucleases. Ribonuclease II (RNase II) is a major, exoribonuclease that intervenes in all of these fundamental processes; it, can act independently or as a component of the exosome, an essential, RNA-degrading multiprotein complex. RNase II-like enzymes are found in all, three kingdoms of life, but there are no structural data for any of the, proteins of this family. Here we report the X-ray crystallographic, structures of both the ligand-free (at 2.44 A resolution) and RNA-bound, (at 2.74 A resolution) forms of Escherichia coli RNase II. In contrast to, sequence predictions, the structures show that RNase II is ... [(full description)]
About this Structure
2IX0 is a [Single protein] structure of sequence from [Escherichia coli] with MG, CA and C5P as [ligands]. Active as [Exoribonuclease II], with EC number [3.1.13.1]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex., Frazao C, McVey CE, Amblar M, Barbas A, Vonrhein C, Arraiano CM, Carrondo MA, Nature. 2006 Sep 7;443(7107):110-4. PMID:16957732
Page seeded by OCA on Tue Oct 30 12:56:51 2007
Categories: Escherichia coli | Exoribonuclease II | Single protein | Amblar, M. | Arraiano, C.M. | Barbas, A | Carrondo, M.A. | Frazao, C. | Mcvey, C.E. | Vonrhein, C. | C5P | CA | MG | Csd | Exonuclease | Hydrolase | Nuclease | Rna | Rna-binding | Rnase ii | Rnb | S1
