3nv8
From Proteopedia
(Difference between revisions)
m (Protected "3nv8" [edit=sysop:move=sysop]) |
Revision as of 06:52, 22 February 2012
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free)
Template:ABSTRACT PUBMED 20667835
About this Structure
3nv8 is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Webby CJ, Jiao W, Hutton RD, Blackmore NJ, Baker HM, Baker EN, Jameson GB, Parker EJ. Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Biol Chem. 2010 Oct 1;285(40):30567-76. Epub 2010 Jul 27. PMID:20667835 doi:10.1074/jbc.M110.111856
- Webby CJ, Baker HM, Lott JS, Baker EN, Parker EJ. The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. J Mol Biol. 2005 Dec 9;354(4):927-39. Epub 2005 Oct 21. PMID:16288916 doi:10.1016/j.jmb.2005.09.093
Categories: 3-deoxy-7-phosphoheptulonate synthase | Mycobacterium tuberculosis | Baker, E N. | Baker, H M. | Hutton, R H. | Jameson, G B. | Jiao, W. | Parker, E J. | Webby, C J. | Aldolase | Aromatic amino-acid biosynthesis | Augmented tim-barrel structure | Cytosol | Dah7p synthase | Evolutionary relationship | Shikimate pathway | Tim barrel | Transferase
