4dfu
From Proteopedia
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[[Category: Minasov, G.]] | [[Category: Minasov, G.]] | ||
[[Category: Savchenko, A.]] | [[Category: Savchenko, A.]] | ||
| + | [[Category: Shakya, T.]] | ||
[[Category: Stogios, P J.]] | [[Category: Stogios, P J.]] | ||
| + | [[Category: Wright, G D.]] | ||
[[Category: Aminoglycoside phosphotransferase]] | [[Category: Aminoglycoside phosphotransferase]] | ||
[[Category: Aminoglycoside]] | [[Category: Aminoglycoside]] | ||
Revision as of 06:54, 22 February 2012
Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin
Template:ABSTRACT PUBMED 22195561
About this Structure
4dfu is a 2 chain structure with sequence from Enterococcus casseliflavus and Streptomyces kanamyceticus. This structure supersedes the now removed PDB entries and 3r82. Full crystallographic information is available from OCA.
Reference
- Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. A small molecule discrimination map of the antibiotic resistance kinome. Chem Biol. 2011 Dec 23;18(12):1591-601. PMID:22195561 doi:10.1016/j.chembiol.2011.10.018
Categories: Enterococcus casseliflavus | Streptomyces kanamyceticus | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Dong, A. | Egorova, E. | Evdokimova, E. | Leo, R Di. | Li, H. | Minasov, G. | Savchenko, A. | Shakya, T. | Stogios, P J. | Wright, G D. | Aminoglycoside phosphotransferase | Aminoglycoside | Antibotic | Center for structural genomics of infectious disease | Csgid | Eukaryotic protein kinase-like fold | Flavanoid | Intracellular | Kanamycin | Kinase | Quercetin | Structural genomic | Transferase | Transferase-antibiotic-inhibitor complex | Transferase-antibotic-inhibitor complex
