3u6j
From Proteopedia
(Difference between revisions)
m (Protected "3u6j" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | [[Image:3u6j.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3u6j", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3u6j| PDB=3u6j | SCENE= }} | ||
| - | + | ===Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor=== | |
| - | + | ||
| + | ==About this Structure== | ||
| + | [[3u6j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U6J OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022320327</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Receptor protein-tyrosine kinase]] | ||
| + | [[Category: Gu, Y.]] | ||
| + | [[Category: Long, A.]] | ||
| + | [[Category: Rose, P.]] | ||
| + | [[Category: Whittington, D A.]] | ||
| + | [[Category: Zhao, H.]] | ||
| + | [[Category: Angiogenesis]] | ||
| + | [[Category: Cancer]] | ||
| + | [[Category: Flk-1]] | ||
| + | [[Category: Kdr]] | ||
| + | [[Category: Phosphotransferase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
| + | [[Category: Transferase/transferase inhibitor]] | ||
| + | [[Category: Vascular endothelial growth factor]] | ||
Revision as of 07:49, 22 February 2012
Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor
About this Structure
3u6j is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu L, Norman MH, Lee M, Xi N, Siegmund A, Boezio AA, Booker S, Choquette D, D'Angelo ND, Germain J, Yang K, Yang Y, Zhang Y, Bellon SF, Whittington DA, Harmange JC, Dominguez C, Kim TS, Dussault I. Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series. J Med Chem. 2012 Feb 24. PMID:22320327 doi:http://dx.doi.org/10.1021/jm201331s
