2fs4

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{{Seed}}
 
[[Image:2fs4.png|left|200px]]
[[Image:2fs4.png|left|200px]]
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{{ABSTRACT_PUBMED_16480874}}
{{ABSTRACT_PUBMED_16480874}}
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==Disease==
 
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Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]]
 
==About this Structure==
==About this Structure==
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2FS4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FS4 OCA].
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[[2fs4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FS4 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16480874</ref><references group="xtra"/>
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<ref group="xtra">PMID:016480874</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Renin]]
[[Category: Renin]]
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[[Category: Bryantb, J.]]
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[[Category: Bryant, J.]]
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[[Category: C.]]
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[[Category: Cai, C.]]
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[[Category: Caia, C.]]
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[[Category: Cheng, X M.]]
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[[Category: Chenga, X M.]]
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[[Category: Cody, W L.]]
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[[Category: Codya, W L.]]
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[[Category: Downing, D M.]]
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[[Category: Downinga, D M.]]
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[[Category: Edmunds, J J.]]
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[[Category: Edmundsa, J J.]]
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[[Category: Erasga, N.]]
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[[Category: Erasgaa, N.]]
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[[Category: Hall, E.]]
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[[Category: Hallc, E.]]
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[[Category: Holsworth, D D.]]
[[Category: Holsworth, D D.]]
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[[Category: Jalaiea, M.]]
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[[Category: Jalaie, M.]]
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[[Category: Kasanic, A.]]
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[[Category: Kasani, A.]]
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[[Category: Leea]]
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[[Category: Lee, C.]]
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[[Category: Lic, T.]]
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[[Category: Li, T.]]
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[[Category: Maitic, S.]]
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[[Category: Maiti, S.]]
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[[Category: McConnella, P.]]
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[[Category: McConnell, P.]]
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[[Category: Powella, N A.]]
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[[Category: Powell, N A.]]
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[[Category: Rahimc, M.]]
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[[Category: Rahim, M.]]
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[[Category: Ryanb, M J.]]
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[[Category: Ryan, M J.]]
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[[Category: Stiera, M.]]
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[[Category: Stier, M.]]
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[[Category: Subedic, R.]]
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[[Category: Subedi, R.]]
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[[Category: Zhanga, E.]]
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[[Category: Zhang, E.]]
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[[Category: Hydrolase]]
[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:44:05 2009''
 

Revision as of 07:46, 29 February 2012

Image:2fs4.png

Template:STRUCTURE 2fs4

Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring

Template:ABSTRACT PUBMED 16480874

About this Structure

2fs4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Holsworth DD, Cai C, Cheng XM, Cody WL, Downing DM, Erasga N, Lee C, Powell NA, Edmunds JJ, Stier M, Jalaie M, Zhang E, McConnell P, Ryan MJ, Bryant J, Li T, Kasani A, Hall E, Subedi R, Rahim M, Maiti S. Ketopiperazine-based renin inhibitors: optimization of the "C" ring. Bioorg Med Chem Lett. 2006 May 1;16(9):2500-4. Epub 2006 Feb 15. PMID:16480874 doi:http://dx.doi.org/10.1016/j.bmcl.2006.01.084

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OCA

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