3sls
From Proteopedia
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| - | + | [[Image:3sls.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3sls", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_3sls| PDB=3sls | SCENE= }} | ||
| - | + | ===Crystal Structure of human MEK-1 kinase in complex with UCB1353770 and AMPPNP=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22245778}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22245778 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22245778}} | ||
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| + | ==About this Structure== | ||
| + | [[3sls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SLS OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022245778</ref><ref group="xtra">PMID:022119475</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Mitogen-activated protein kinase kinase]] | ||
| + | [[Category: Ceska, T A.]] | ||
| + | [[Category: Meier, C.]] | ||
| + | [[Category: Serine-threonine kinase]] | ||
| + | [[Category: Signalling]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 08:44, 29 February 2012
Crystal Structure of human MEK-1 kinase in complex with UCB1353770 and AMPPNP
Template:ABSTRACT PUBMED 22245778
About this Structure
3sls is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Meier C, Brookings DC, Ceska TA, Doyle C, Gong H, McMillan D, Saville GP, Mushtaq A, Knight D, Reich S, Pearl LH, Powell KA, Savva R, Allen RA. Engineering human MEK-1 for structural studies: A case study of combinatorial domain hunting. J Struct Biol. 2012 Feb;177(2):329-34. Epub 2012 Jan 8. PMID:22245778 doi:10.1016/j.jsb.2012.01.002
- Laing VE, Brookings DC, Carbery RJ, Simorte JG, Hutchings MC, Langham BJ, Lowe MA, Allen RA, Fetterman JR, Turner J, Meier C, Kennedy J, Merriman M. Fused thiophene derivatives as MEK inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):472-5. Epub 2011 Nov 6. PMID:22119475 doi:10.1016/j.bmcl.2011.10.105
