Chromodomain-helicase-DNA-binding protein
From Proteopedia
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(New page: {{STRUCTURE_2b2u| PDB=2b2u | SIZE=400| SCENE= |right|CAPTION=human CHD1 complex with histone H3 tail peptide 2b2u}} <!-- Please use the "3D" button above this box to insert a Jmol ...)
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Revision as of 11:14, 4 March 2012
Chromodomain-helicase-DNA-binding protein (CHD) remodel chromatin and histone deacylation thus affecting transcription. Chromatin regulation involves the tightness of packing of DNA. When DNA is tightly packed, gene expression is slower.
==3D structures of CHD
2b2t – hCHD1 (mutant) + histone H3 tail – human
2b2u, 2b2v, 2b2w - hCHD1 + histone H3 tail
2b2y - hCHD1
2l5u – hCHD4 PHD finger 1 – NMR
2l75 - hCHD4 PHD finger 2 + histone H3 peptide – NMR
2ee1 – hCHD4 chromodomain – NMR
2epb – hCHD6 chromodomain 2 – NMR
2ckc, 2v0e, 2v0f – hCHD7 BRK domain - NMR
2dl6, 2cka – hCHD8 BRK domain - NMR
