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Sandbox Reserved 429
From Proteopedia
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<Structure load='1m4u' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1m4u' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
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| + | <scene name='Sandbox_Reserved_429/Alec_alphas/1'>alpha helices</scene> | ||
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| + | 1. Basic info (size, ligand name) | ||
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| + | 2. Origin (Zebrafish?) | ||
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| + | 3. Relation to disease (Metastatic Prostate cancer, kidney disease) | ||
| + | |||
| + | 4. Pharmaceutical Applications | ||
===Overall Structure=== | ===Overall Structure=== | ||
Revision as of 05:58, 5 March 2012
| This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439. |
Contents |
YourMacromolecule
Introduction
|
1. Basic info (size, ligand name)
2. Origin (Zebrafish?)
3. Relation to disease (Metastatic Prostate cancer, kidney disease)
4. Pharmaceutical Applications
Overall Structure
Binding Interactions
|
Outline
1. BMP7-Noggin Complex
2.Conformational changes due to binding
3. Hydrophilic and hydrophobic pockets
4. Receptor 1 & 2 and Finger 1 & 2
5. Others Antagonist of BMP 7
6. Binding affinity in comparison to others BMP families
7. Overall Summary of how binding affects overall pathways for bone formation
Additional Features
Credits
Introduction - Alec
Overall Structure - William
Drug Binding Site - Felix
Additional Features - Paula
