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3qe0

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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:016004878</ref><references group="xtra"/>
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<ref group="xtra">PMID:022383884</ref><ref group="xtra">PMID:016004878</ref><references group="xtra"/>
[[Category: Heterotrimeric G-protein GTPase]]
[[Category: Heterotrimeric G-protein GTPase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 05:50, 14 March 2012

Image:3qe0.png

Template:STRUCTURE 3qe0

A Galpha-i1 P-loop mutation prevents transition to the activated state

Template:ABSTRACT PUBMED 22383884

About this Structure

3qe0 is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bosch DE, Willard FS, Ramanujam R, Kimple AJ, Willard MD, Naqvi NI, Siderovski DP. A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis. PLoS Pathog. 2012 Feb;8(2):e1002553. Epub 2012 Feb 23. PMID:22383884 doi:10.1371/journal.ppat.1002553
  • Johnston CA, Willard FS, Jezyk MR, Fredericks Z, Bodor ET, Jones MB, Blaesius R, Watts VJ, Harden TK, Sondek J, Ramer JK, Siderovski DP. Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange. Structure. 2005 Jul;13(7):1069-80. PMID:16004878 doi:10.1016/j.str.2005.04.007

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OCA

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