4dv8

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m (Protected "4dv8" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4dv8.jpg|left|200px]]
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The entry 4dv8 is ON HOLD
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{{STRUCTURE_4dv8| PDB=4dv8 | SCENE= }}
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Authors: Margosiak, S.A., Sankaran, B.
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===Anthrax Lethal Factor metalloproteinase in complex with the Hydroxamic acid based small molecule PT8421===
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Description: Anthrax Lethal Factor metalloproteinase in complex with the Hydroxamic acid based small molecule PT8421
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{{ABSTRACT_PUBMED_22342144}}
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==About this Structure==
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[[4dv8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DV8 OCA].
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==Reference==
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<ref group="xtra">PMID:022342144</ref><references group="xtra"/>
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[[Category: Anthrax lethal factor endopeptidase]]
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[[Category: Bacillus anthracis]]
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[[Category: Margosiak, S A.]]
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[[Category: Sankaran, B.]]
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[[Category: Endopeptidase]]
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[[Category: Hydrolase]]
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[[Category: Zinc dependent]]

Revision as of 06:33, 14 March 2012

Template:STRUCTURE 4dv8

Anthrax Lethal Factor metalloproteinase in complex with the Hydroxamic acid based small molecule PT8421

Template:ABSTRACT PUBMED 22342144

About this Structure

4dv8 is a 1 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

  • Jiao GS, Kim S, Moayeri M, Crown D, Thai A, Cregar-Hernandez L, McKasson L, Sankaran B, Lehrer A, Wong T, Johns L, Margosiak SA, Leppla SH, Johnson AT. Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2242-6. Epub 2012 Feb 1. PMID:22342144 doi:10.1016/j.bmcl.2012.01.095

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