Sphingomyelinase
From Proteopedia
(Difference between revisions)
| Line 15: | Line 15: | ||
[[2ddr]], [[2dds]], [[2ddt]] – BcSMase + cation – ''Bacillus cereus''<br /> | [[2ddr]], [[2dds]], [[2ddt]] – BcSMase + cation – ''Bacillus cereus''<br /> | ||
[[2uyr]] – BcSMase (mutant) | [[2uyr]] – BcSMase (mutant) | ||
| + | |||
| + | [[Category:Topic Page]] | ||
Revision as of 11:41, 14 March 2012
| |||||||||
| Sphingomyelin complex with cobalt ion 2dds | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | |||||||||
| Activity: | Sphingomyelin phosphodiesterase, with EC number 3.1.4.12 | ||||||||
| Related: | 2ddr, 2ddt | ||||||||
| |||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB, TOPSAN | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Sphingomyelinase (SMase) is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide. The SMase is classified into 5 types according to their pH dependence and cation dependence.
3D structures of sphingomyelinase
3rlh, 3rlg – SMase D (mutant) – Loxosceles intermedia
1xx1, 2f9r – SMase I – Loxosceles laeta
1zwx – SMase C – Listeria ivanovii
2ddr, 2dds, 2ddt – BcSMase + cation – Bacillus cereus
2uyr – BcSMase (mutant)
