Lignin peroxidase
From Proteopedia
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Revision as of 11:59, 18 March 2012
Lignin peroxidase (Lip) catalyzes the biodegradation of lignin using hydrogen peroxide. Lignin comprises 20-30% of woody plants cell wall. It is made of branched and heterogenous structure of phenylpropanoid units. It is highly resistant to biodegradation and only higher fungi are capable of degrading it. Veratryl alcohol is the cofactor in this reaction. Lip is used as a skin-lightening active agent.
3D structures of lignin peroxidase
1lga, 1llp, 1qpa, 1b80, 1b82 – PcLip – Phanerochaete chrysosporium
1b85 – PcLip (mutant)
3q3u – Lip – Trametes cervina