3g49

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===N-(Pyridin-2-yl) Arylsulfonamide Inhibitors of 11b-Hydroxysteroid Dehydrogenase Type 1: Discovery of PF-915275===
===N-(Pyridin-2-yl) Arylsulfonamide Inhibitors of 11b-Hydroxysteroid Dehydrogenase Type 1: Discovery of PF-915275===
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{{ABSTRACT_PUBMED_19473839}}
==About this Structure==
==About this Structure==
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3G49 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Cavia_porcellus Cavia porcellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G49 OCA].
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[[3g49]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cavia_porcellus Cavia porcellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G49 OCA].
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==Reference==
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<ref group="xtra">PMID:019473839</ref><references group="xtra"/>
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: Cavia porcellus]]
[[Category: Cavia porcellus]]
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[[Category: Nadp]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase/oxidoreductase inhibitor complex]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Signal-anchor]]
[[Category: Signal-anchor]]
[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 5 10:56:04 2009''
 

Revision as of 06:13, 21 March 2012

Template:STRUCTURE 3g49

N-(Pyridin-2-yl) Arylsulfonamide Inhibitors of 11b-Hydroxysteroid Dehydrogenase Type 1: Discovery of PF-915275

Template:ABSTRACT PUBMED 19473839

About this Structure

3g49 is a 4 chain structure with sequence from Cavia porcellus. Full crystallographic information is available from OCA.

Reference

  • Siu M, Johnson TO, Wang Y, Nair SK, Taylor WD, Cripps SJ, Matthews JJ, Edwards MP, Pauly TA, Ermolieff J, Castro A, Hosea NA, LaPaglia A, Fanjul AN, Vogel JE. N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3493-7. Epub 2009 May 7. PMID:19473839 doi:10.1016/j.bmcl.2009.05.011

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