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2ygf

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{{STRUCTURE_2ygf| PDB=2ygf | SCENE= }}
{{STRUCTURE_2ygf| PDB=2ygf | SCENE= }}
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===L89V, L93I AND V136M MUTANT OF N-TERM HSP90 COMPLEXED WITH GELDANAMYCIN===
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===L89V, L93I and V136M Mutant of N-Term HSP90 complexed with Geldanamycin===

Revision as of 06:32, 21 March 2012

Image:2ygf.png

Template:STRUCTURE 2ygf

L89V, L93I and V136M Mutant of N-Term HSP90 complexed with Geldanamycin

Template:ABSTRACT PUBMED 21778327

About this Structure

2ygf is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW. Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90. FASEB J. 2011 Nov;25(11):3828-37. Epub 2011 Jul 21. PMID:21778327 doi:10.1096/fj.11-188821

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OCA

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