2bvg
From Proteopedia
(New page: 200px<br /> <applet load="2bvg" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bvg, resolution 3.18Å" /> '''CRYSTAL STRUCTURE O...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2BVG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Arthrobacter_nicotinovorans Arthrobacter nicotinovorans]] with FAD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.6 1.5.3.6]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BVG OCA]]. | + | 2BVG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Arthrobacter_nicotinovorans Arthrobacter nicotinovorans]] with FAD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/(R)-6-hydroxynicotine_oxidase (R)-6-hydroxynicotine oxidase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.6 1.5.3.6]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BVG OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of 6-hydroxy-D-nicotine oxidase from Arthrobacter nicotinovorans., Koetter JW, Schulz GE, J Mol Biol. 2005 Sep 16;352(2):418-28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16095622 16095622] | Crystal structure of 6-hydroxy-D-nicotine oxidase from Arthrobacter nicotinovorans., Koetter JW, Schulz GE, J Mol Biol. 2005 Sep 16;352(2):418-28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16095622 16095622] | ||
| + | [[Category: (R)-6-hydroxynicotine oxidase]] | ||
[[Category: Arthrobacter nicotinovorans]] | [[Category: Arthrobacter nicotinovorans]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: oxidase]] | [[Category: oxidase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:02:46 2007'' |
Revision as of 10:58, 30 October 2007
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CRYSTAL STRUCTURE OF 6-HYDOXY-D-NICOTINE OXIDASE FROM ARTHROBACTER NICOTINOVORANS. CRYSTAL FORM 1 (P21)
Overview
The crystal structure of 6-hydroxy-d-nicotine oxidase (EC 1.5.3.6) was, solved by X-ray diffraction analysis in three crystal forms at resolutions, up to 1.9 A. The enzyme is monomeric in solution and also in the mother, liquor but formed disulfide-dimers in all crystals. It belongs to the, p-cresol methylhydroxylase-vanillyl-alcohol oxidase family and contains an, FAD covalently bound to the polypeptide. The covalent bond of this enzyme, was the first for which a purely autocatalytic formation had been shown., In contrast to previous reports, the bond does not involve N(epsilon2), (N3) of His72 but the N(delta1) (N1) atom. The geometry of this reaction, is proposed and the autoflavinylation is discussed in the light of, homologous structures. The enzyme is specific for ... [(full description)]
About this Structure
2BVG is a [Single protein] structure of sequence from [Arthrobacter nicotinovorans] with FAD as [ligand]. Active as [(R)-6-hydroxynicotine oxidase], with EC number [1.5.3.6]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of 6-hydroxy-D-nicotine oxidase from Arthrobacter nicotinovorans., Koetter JW, Schulz GE, J Mol Biol. 2005 Sep 16;352(2):418-28. PMID:16095622
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