4dfg

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'''Unreleased structure'''
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[[Image:4dfg.jpg|left|200px]]
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The entry 4dfg is ON HOLD until Paper Publication
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{{STRUCTURE_4dfg| PDB=4dfg | SCENE= }}
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Authors: Wang, Y.-F., Agniswamy, J., Weber, I.T.
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===Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A===
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Description: Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro-furanyl Urethanes as P2-ligand, GRL-0249A
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{{ABSTRACT_PUBMED_22364812}}
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==About this Structure==
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[[4dfg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFG OCA].
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==Reference==
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<ref group="xtra">PMID:022364812</ref><references group="xtra"/>
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[[Category: HIV-1 retropepsin]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Agniswamy, J.]]
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[[Category: Wang, Y F.]]
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[[Category: Weber, I T.]]
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[[Category: Aspartic acid protease]]
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[[Category: Cyclopentyltetrahydro- furanyl urethanes p2-ligand]]
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[[Category: Hiv-1 protease inhibitor grl-0249a]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Wild-type hiv-1 protease]]

Revision as of 07:34, 21 March 2012

Image:4dfg.jpg

Template:STRUCTURE 4dfg

Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A

Template:ABSTRACT PUBMED 22364812

About this Structure

4dfg is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ghosh AK, Chapsal BD, Steffey M, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H. Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2308-11. Epub 2012 Feb 2. PMID:22364812 doi:10.1016/j.bmcl.2012.01.061

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OCA

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