This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4dfg
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | [[Image:4dfg.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_4dfg", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_4dfg| PDB=4dfg | SCENE= }} | ||
| - | + | ===Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22364812}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22364812 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_22364812}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[4dfg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFG OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022364812</ref><references group="xtra"/> | ||
| + | [[Category: HIV-1 retropepsin]] | ||
| + | [[Category: Human immunodeficiency virus 1]] | ||
| + | [[Category: Agniswamy, J.]] | ||
| + | [[Category: Wang, Y F.]] | ||
| + | [[Category: Weber, I T.]] | ||
| + | [[Category: Aspartic acid protease]] | ||
| + | [[Category: Cyclopentyltetrahydro- furanyl urethanes p2-ligand]] | ||
| + | [[Category: Hiv-1 protease inhibitor grl-0249a]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Wild-type hiv-1 protease]] | ||
Revision as of 07:34, 21 March 2012
Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A
Template:ABSTRACT PUBMED 22364812
About this Structure
4dfg is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Ghosh AK, Chapsal BD, Steffey M, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H. Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2308-11. Epub 2012 Feb 2. PMID:22364812 doi:10.1016/j.bmcl.2012.01.061
