4dem

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'''Unreleased structure'''
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[[Image:4dem.jpg|left|200px]]
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The entry 4dem is ON HOLD until Paper Publication
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{{STRUCTURE_4dem| PDB=4dem | SCENE= }}
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Authors: Park, J., Lin, Y.-S., Tsantrizos, Y.S., Berghuis, A.M.
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===Crystal structure of human FPPS in complex with YS_04_70===
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Description: Crystal structure of human FPPS in complex with YS_04_70
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{{ABSTRACT_PUBMED_22390415}}
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==About this Structure==
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[[4dem]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEM OCA].
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==Reference==
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<ref group="xtra">PMID:022390415</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Berghuis, A M.]]
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[[Category: Lin, Y S.]]
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[[Category: Park, J.]]
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[[Category: Tsantrizos, Y S.]]
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[[Category: Bisphosphonate]]
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[[Category: Cholesterol biosynthesis]]
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[[Category: Isoprene biosynthesis]]
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[[Category: Mevalonate pathway]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 07:37, 21 March 2012

Template:STRUCTURE 4dem

Crystal structure of human FPPS in complex with YS_04_70

Template:ABSTRACT PUBMED 22390415

About this Structure

4dem is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lin YS, Park J, De Schutter JW, Huang XF, Berghuis AM, Sebag M, Tsantrizos YS. Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. J Med Chem. 2012 Mar 19. PMID:22390415 doi:10.1021/jm201657x

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