3uzc

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'''Unreleased structure'''
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[[Image:3uzc.jpg|left|200px]]
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The entry 3uzc is ON HOLD until Paper Publication
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{{STRUCTURE_3uzc| PDB=3uzc | SCENE= }}
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Authors: Congreve, M., Andrews, S.P., Dore, A.S., Hollenstein, K., Hurrell, E., Langmead, C.J., Mason, J.S., Ng, I.W., Zhukov, A., Weir, M., Marshall, F.H.
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===Thermostabilised Adenosine A2A receptor in complex with 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol===
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Description: Thermostabilised Adenosine A2A receptor in complex with compound 4E
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{{ABSTRACT_PUBMED_22220592}}
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==About this Structure==
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[[3uzc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZC OCA].
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==Reference==
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<ref group="xtra">PMID:022220592</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Andrews, S P.]]
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[[Category: Congreve, M.]]
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[[Category: Dore, A S.]]
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[[Category: Hollenstein, K.]]
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[[Category: Hurrell, E.]]
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[[Category: Langmead, C J.]]
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[[Category: Marshall, F H.]]
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[[Category: Mason, J S.]]
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[[Category: Ng, I W.]]
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[[Category: Weir, M.]]
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[[Category: Zhukov, A.]]
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[[Category: 7tm]]
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[[Category: G-protein]]
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[[Category: Gpcr]]
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[[Category: Membrane protein]]
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[[Category: Signaling protein]]

Revision as of 07:38, 21 March 2012

Image:3uzc.jpg

Template:STRUCTURE 3uzc

Thermostabilised Adenosine A2A receptor in complex with 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol

Template:ABSTRACT PUBMED 22220592

About this Structure

3uzc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Congreve M, Andrews SP, Dore AS, Hollenstein K, Hurrell E, Langmead CJ, Mason JS, Ng IW, Tehan B, Zhukov A, Weir M, Marshall FH. Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design. J Med Chem. 2012 Mar 8;55(5):1898-903. Epub 2012 Jan 27. PMID:22220592 doi:10.1021/jm201376w

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OCA

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