This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3oni
From Proteopedia
m (Protected "3oni" [edit=sysop:move=sysop]) |
|||
| Line 9: | Line 9: | ||
{{STRUCTURE_3oni| PDB=3oni | SCENE= }} | {{STRUCTURE_3oni| PDB=3oni | SCENE= }} | ||
| - | ===Crystal Structure of the second bromodomain of | + | ===Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor JQ1=== |
| Line 22: | Line 22: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020871596</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
| Line 34: | Line 34: | ||
[[Category: SGC, Structural Genomics Consortium.]] | [[Category: SGC, Structural Genomics Consortium.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| + | [[Category: Bromodomain]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Inhibition]] | ||
| + | [[Category: Probe]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Structural genomics consortium]] | ||
Revision as of 06:57, 28 March 2012
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor JQ1
Template:ABSTRACT PUBMED 20871596
About this Structure
3oni is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. Selective inhibition of BET bromodomains. Nature. 2010 Sep 24. PMID:20871596 doi:10.1038/nature09504
Categories: Homo sapiens | Arrowsmith, C H. | Bountra, C. | Bradner, J E. | Delft, F von. | Edwards, A M. | Fedorov, O. | Filippakopoulos, P. | Picaud, S. | SGC, Structural Genomics Consortium. | Weigelt, J. | Bromodomain | Cell cycle | Inhibition | Probe | Sgc | Structural genomic | Structural genomics consortium
