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2yim
From Proteopedia
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| - | + | [[Image:2yim.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_2yim", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
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| + | {{STRUCTURE_2yim| PDB=2yim | SCENE= }} | ||
| - | + | ===The enolisation chemistry of a thioester-dependent racemase: the 1.4 A crystal structure of a complex with a planar reaction intermediate analogue=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22360758}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22360758 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22360758}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[2yim]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YIM OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022360758</ref><ref group="xtra">PMID:017320106</ref><references group="xtra"/> | ||
| + | [[Category: Alpha-methylacyl-CoA racemase]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Bhaumik, P.]] | ||
| + | [[Category: Conzelmann, E.]] | ||
| + | [[Category: Hiltunen, J K.]] | ||
| + | [[Category: Juffer, A H.]] | ||
| + | [[Category: Sharma, S.]] | ||
| + | [[Category: Venkatesan, R.]] | ||
| + | [[Category: Wierenga, R K.]] | ||
| + | [[Category: Isomerase]] | ||
| + | [[Category: Methyl-coa racemase]] | ||
| + | [[Category: Molecular dynamic]] | ||
| + | [[Category: Oxyanion hole]] | ||
| + | [[Category: Qm/mm]] | ||
| + | [[Category: Transition state]] | ||
Revision as of 07:39, 28 March 2012
The enolisation chemistry of a thioester-dependent racemase: the 1.4 A crystal structure of a complex with a planar reaction intermediate analogue
Template:ABSTRACT PUBMED 22360758
About this Structure
2yim is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sharma S, Bhaumik P, Schmitz W, Venkatesan R, Hiltunen JK, Conzelmann E, Juffer AH, Wierenga RK. The Enolization Chemistry of a Thioester-Dependent Racemase: The 1.4 A Crystal Structure of a Reaction Intermediate Complex Characterized by Detailed QM/MM Calculations. J Phys Chem B. 2012 Mar 22;116(11):3619-29. Epub 2012 Mar 7. PMID:22360758 doi:10.1021/jp210185m
- Bhaumik P, Schmitz W, Hassinen A, Hiltunen JK, Conzelmann E, Wierenga RK. The catalysis of the 1,1-proton transfer by alpha-methyl-acyl-CoA racemase is coupled to a movement of the fatty acyl moiety over a hydrophobic, methionine-rich surface. J Mol Biol. 2007 Apr 6;367(4):1145-61. Epub 2007 Jan 27. PMID:17320106 doi:http://dx.doi.org/10.1016/j.jmb.2007.01.062
