1i0e
From Proteopedia
(New page: 200px<br /> <applet load="1i0e" size="450" color="white" frame="true" align="right" spinBox="true" caption="1i0e, resolution 3.50Å" /> '''CRYSTAL STRUCTURE O...) |
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caption="1i0e, resolution 3.50Å" /> | caption="1i0e, resolution 3.50Å" /> | ||
'''CRYSTAL STRUCTURE OF CREATINE KINASE FROM HUMAN MUSCLE'''<br /> | '''CRYSTAL STRUCTURE OF CREATINE KINASE FROM HUMAN MUSCLE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1I0E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] Full crystallographic information is available from [http:// | + | 1I0E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0E OCA]. |
==Reference== | ==Reference== | ||
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[[Category: double helix]] | [[Category: double helix]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 15:59:00 2008'' |
Revision as of 13:59, 15 February 2008
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CRYSTAL STRUCTURE OF CREATINE KINASE FROM HUMAN MUSCLE
Overview
The crystal structure of human muscle creatine kinase has been determined, by the molecular-replacement method and refined at 3.5A resolution. The, structures of both the monomer and the dimer closely resemble those of the, other known structures in the creatine kinase family. Two types of dimers, one with a non-crystallographic twofold symmetry axis and the other with a, crystallographic twofold symmetry axis, were found to exist simultaneously, in the crystal. These dimers form an infinite "double-helix"-like, structure along an unusual long crystallographic 3(1) axis.
About this Structure
1I0E is a Single protein structure of sequence from Homo sapiens. Active as Creatine kinase, with EC number 2.7.3.2 Full crystallographic information is available from OCA.
Reference
Structure of human muscle creatine kinase., Shen YQ, Tang L, Zhou HM, Lin ZJ, Acta Crystallogr D Biol Crystallogr. 2001 Aug;57(Pt 8):1196-200. PMID:11517911
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