3aox

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===X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802===
===X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802===
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The line below this paragraph, {{ABSTRACT_PUBMED_21575866}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21575866 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21575866}}
==About this Structure==
==About this Structure==
[[3aox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AOX OCA].
[[3aox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AOX OCA].
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==Reference==
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<ref group="xtra">PMID:021575866</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Moertl, M.]]
[[Category: Moertl, M.]]
[[Category: Nagel, S.]]
[[Category: Nagel, S.]]
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[[Category: Alk kinase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:07, 4 April 2012

Template:STRUCTURE 3aox

X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802

Template:ABSTRACT PUBMED 21575866

About this Structure

3aox is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sakamoto H, Tsukaguchi T, Hiroshima S, Kodama T, Kobayashi T, Fukami TA, Oikawa N, Tsukuda T, Ishii N, Aoki Y. CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer Cell. 2011 May 17;19(5):679-90. PMID:21575866 doi:10.1016/j.ccr.2011.04.004

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