2jhp

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(New page: 200px<br /> <applet load="2jhp" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jhp, resolution 2.50&Aring;" /> '''THE STRUCTURE OF BL...)
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==About this Structure==
==About this Structure==
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2JHP is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)]] with SAH and GUN as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JHP OCA]].
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2JHP is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)]] with SAH and GUN as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JHP OCA]].
==Reference==
==Reference==
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[[Category: virion protein]]
[[Category: virion protein]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 20:09:24 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:05:45 2007''

Revision as of 11:01, 30 October 2007


2jhp, resolution 2.50Å

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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE

Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series, of four chemical reactions. Some viruses achieve this using a single, molecule; the crystal structure of such an enzyme from bluetongue virus, reveals an elongated modular architecture that provides a scaffold for an, assemblage of active sites, two contributed by a domain of novel, structure.

About this Structure

2JHP is a [Single protein] structure of sequence from [Bluetongue virus 10 (isolate usa)] with SAH and GUN as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654

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