Carbonyl reductase
From Proteopedia
(Difference between revisions)
Michal Harel (Talk | contribs)
(New page: <!-- Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page. Or use the four-green-boxes-button to insert scrollable text adjacent to a Jmol applet. Che...)
Next diff →
Revision as of 09:05, 10 April 2012
Carbonyl reductase (CBR) catalyzes the reaction converting R-CHOH-R and NADP to R-CO-R’ and NADPH. CBR has wide substrate specificity oxidoreductase activity. CBR has similar properties to aldose reductase and aldehyde reductase.
3D structures of carbonyl reductase
1zze – CBR – Sporidiobolus salmonicolor
3ctm – CBR – Candida parapsilosis
Carbonyl reductase binary complex with NADPH
3bhi - hCBR1 + NADPH - human
2hrb – hCBR3 + NADPH
Carbonyl reductase ternary complex with NADPH
1cyd – CBR + 2-propanot + NADPH – mouse
1wma – hCBR1 + hydroxyl-PP + NADPH
2pfg - hCBR1 + bicycle-undecane + NADPH
3bhj - hCBR1 + glutathione + NADPH
3bhm - hCBR1 + hydroxymethylglutathione + NADPH
