3s85

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'''Unreleased structure'''
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[[Image:3s85.jpg|left|200px]]
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The entry 3s85 is ON HOLD until Paper Publication
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{{STRUCTURE_3s85| PDB=3s85 | SCENE= }}
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Authors: DeGoey, D.A., Flosi, W.J., Grampovnik, D.J., Flentge, C.A.
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===Discovery of New HIV Protease Inhibitors with Potential for Convenient Dosing and Reduced Side Effects: A-790742 and A-792611.===
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Description: Discovery of New HIV Protease Inhibitors with Potential for Convenient Dosing and Reduced Side Effects: A-790742 and A-792611.
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{{ABSTRACT_PUBMED_19323562}}
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==About this Structure==
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[[3s85]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S85 OCA].
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==Reference==
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<ref group="xtra">PMID:019323562</ref><references group="xtra"/>
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[[Category: Human immunodeficiency virus 1]]
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[[Category: DeGoey, D A.]]
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[[Category: Flentge, C A.]]
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[[Category: Flosi, W J.]]
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[[Category: Grampovnik, D J.]]
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[[Category: Acid protease]]
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[[Category: Aspartic-type endopepidase activity]]
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[[Category: Beta barrel]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 06:57, 11 April 2012

Template:STRUCTURE 3s85

Discovery of New HIV Protease Inhibitors with Potential for Convenient Dosing and Reduced Side Effects: A-790742 and A-792611.

Template:ABSTRACT PUBMED 19323562

About this Structure

3s85 is a 12 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Degoey DA, Grampovnik DJ, Flentge CA, Flosi WJ, Chen HJ, Yeung CM, Randolph JT, Klein LL, Dekhtyar T, Colletti L, Marsh KC, Stoll V, Mamo M, Morfitt DC, Nguyen B, Schmidt JM, Swanson SJ, Mo H, Kati WM, Molla A, Kempf DJ. 2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects. J Med Chem. 2009 Apr 23;52(8):2571-86. PMID:19323562 doi:http://dx.doi.org/10.1021/jm900044w

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