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4dst
From Proteopedia
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Revision as of 07:11, 18 April 2012
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Template:ABSTRACT PUBMED 22431598
About this Structure
4dst is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Mar 19. PMID:22431598 doi:10.1073/pnas.1116510109
Categories: Homo sapiens | Anderson, D J. | Bowman, K K. | Fang, G. | Fauber, B P. | Garrenton, L S. | Giannetti, A M. | Jackson, P K. | Ludlam, M. | Malek, S. | Maurer, T. | Mellman, I. | Oh, A. | Pan, B. | Pitts, K. | Ruldolph, J. | Skelton, N J. | Starovasnik, M A. | Stokoe, D. | Wang, W. | Wu, J. | Hydrolase | Signaling | Small g-protein
