3sym

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Revision as of 07:13, 18 April 2012

Template:STRUCTURE 3sym

Glycogen Phosphorylase b in complex with 3 -C-(hydroxymethyl)-beta-D-glucopyranonucleoside of 5-fluorouracil

Template:ABSTRACT PUBMED 22296957

About this Structure

3sym is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

• Manta S, Xipnitou A, Kiritsis C, Kantsadi AL, Hayes JM, Skamnaki VT, Lamprakis C, Kontou M, Zoumpoulakis P, Zographos SE, Leonidas DD, Komiotis D. 3'-axial CH(2) OH substitution on glucopyranose does not increase glycogen phosphorylase inhibitory potency. QM/MM-PBSA calculations suggest why. Chem Biol Drug Des. 2012 Feb 2. doi: 10.1111/j.1747-0285.2012.01349.x. PMID:22296957 doi:10.1111/j.1747-0285.2012.01349.x