Sandbox SouthUniversity3

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Current revision (14:42, 18 April 2012) (edit) (undo)
 
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Viral DNA is highlighted here as a <scene name='Sandbox_SouthUniversity3/Human_dna_ribbon/1'>brown ribbon</scene>
Viral DNA is highlighted here as a <scene name='Sandbox_SouthUniversity3/Human_dna_ribbon/1'>brown ribbon</scene>
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One strand of human DNA can be seen here <scene name='Sandbox_SouthUniversity3/Human-viral_dna_ribbon/3'>highlighted in green</scene>
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One strand of human DNA can be seen here <scene name='Sandbox_SouthUniversity3/Human-viral_dna_ribbon/3'>highlighted in green</scene>. Note that one of the (brown) viral DNA strands is oriented close to and perpendicular to the human (green) strand
The drug raltegravir (Isentress)is the first drug that has made its way to market that acts as an inhibitor of HIV-integrase. It is shown <scene name='Sandbox_SouthUniversity3/Isentress_spacefill/1'>here</scene> displayed in a space filling representation.It is easier to see the functional groups displayed as <scene name='Sandbox_SouthUniversity3/Isentress_sticks/1'>sticks</scene>
The drug raltegravir (Isentress)is the first drug that has made its way to market that acts as an inhibitor of HIV-integrase. It is shown <scene name='Sandbox_SouthUniversity3/Isentress_spacefill/1'>here</scene> displayed in a space filling representation.It is easier to see the functional groups displayed as <scene name='Sandbox_SouthUniversity3/Isentress_sticks/1'>sticks</scene>

Current revision

==Integrase as an anti-HIV drug target==

Structure of integrase in action (PDB entry 3os1)

Drag the structure with the mouse to rotate
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