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4d9t

From Proteopedia

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'''Unreleased structure'''
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[[Image:4d9t.jpg|left|200px]]
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The entry 4d9t is ON HOLD until Paper Publication
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{{STRUCTURE_4d9t| PDB=4d9t | SCENE= }}
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Authors: Serafimova, I.M., Pufall, M.A., Krishnan, S., Duda, K., Cohen, M.S., Maglathlin, R.L., McFarland, J.M., Miller, R.M., Frodin, M., Taunton, J.
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===Rsk2 C-terminal Kinase Domain with inhibitor (E)-methyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate===
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Description: Rsk2 C-terminal Kinase Domain with inhibitor (E)-methyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate
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{{ABSTRACT_PUBMED_22466421}}
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==About this Structure==
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[[4d9t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D9T OCA].
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==Reference==
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<ref group="xtra">PMID:022466421</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Cohen, M S.]]
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[[Category: Duda, K.]]
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[[Category: Frodin, M.]]
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[[Category: Krishnan, S.]]
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[[Category: Maglathlin, R L.]]
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[[Category: McFarland, J M.]]
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[[Category: Miller, R M.]]
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[[Category: Pufall, M A.]]
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[[Category: Serafimova, I M.]]
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[[Category: Taunton, J.]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Migration]]
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[[Category: Phosphorylation]]
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[[Category: Reversible]]
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[[Category: Thiol]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 09:11, 25 April 2012

Image:4d9t.jpg

Template:STRUCTURE 4d9t

Rsk2 C-terminal Kinase Domain with inhibitor (E)-methyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate

Template:ABSTRACT PUBMED 22466421

About this Structure

4d9t is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Serafimova IM, Pufall MA, Krishnan S, Duda K, Cohen MS, Maglathlin RL, McFarland JM, Miller RM, Frodin M, Taunton J. Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nat Chem Biol. 2012 Apr 1;8(5):471-6. doi: 10.1038/nchembio.925. PMID:22466421 doi:10.1038/nchembio.925

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OCA

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