This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6-phosphogluconate dehydrogenase
From Proteopedia
| Line 37: | Line 37: | ||
[[2iyp]] - Ll6PDH + ADP + ribulose 5-phosphate + NADP<BR /> | [[2iyp]] - Ll6PDH + ADP + ribulose 5-phosphate + NADP<BR /> | ||
[[2iz0]] - Ll6PDH + inhibitor + ADP + NADP<BR /> | [[2iz0]] - Ll6PDH + inhibitor + ADP + NADP<BR /> | ||
| + | |||
| + | [[Category:Topic Page]] | ||
Revision as of 10:55, 2 May 2012
Template:STRUCTURE 1pgo 6-phosphogluconate dehydrogenase (6PDH) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.
3D structures of 6-phosphogluconate dehydrogenase
2pgd - s6PDH – sheep
1pgj - 6PDH – Trypanosoma brucei
2p4q - 6PDH – yeast
2zyg - 6PDH (mutant) – Klebsiella pneumonia
4e21 - 6PDH – Geobacter metallireducens
6PDH binary complex
1pgn – s6PDH + Br-NADP
1pgo - s6PDH + NADP
1pgp - s6PDH + 6PG
1pgq - s6PDH + AMP
2jkv - 6PDH + NADP – human
2zya - Ec6PDH (mutant) + 6PG – Escherichia coli
2w8z, 2w90 - 6PDH + 6PG – Geobacillus stearothermophilus
2iyo - Ll6PDH + 6PG – Lactococcus lactis
2zyd - Ec6PDH (mutant) + glucose
6PDH ternary complex
2iz1 - Ll6PDH + inhibitor + ADP
3fwn - Ec6PDH (mutant) + ADP + 6PG
6PDH quaternary complex
2iyp - Ll6PDH + ADP + ribulose 5-phosphate + NADP
2iz0 - Ll6PDH + inhibitor + ADP + NADP
