2wvj

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{{STRUCTURE_2wvj| PDB=2wvj | SCENE= }}
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===MUTATION OF THR163 TO SER IN HUMAN THYMIDINE KINASE SHIFTS THE SPECIFICITY FROM THYMIDINE TOWARDS THE NUCLEOSIDE ANALOGUE AZIDOTHYMIDINE===
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===Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine===
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{{ABSTRACT_PUBMED_22385435}}
==About this Structure==
==About this Structure==
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2WVJ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVJ OCA].
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[[2wvj]] is a 8 chain structure of [[Thymidine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVJ OCA].
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==See Also==
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*[[Thymidine kinase|Thymidine kinase]]
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==Reference==
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<ref group="xtra">PMID:022385435</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thymidine kinase]]
[[Category: Thymidine kinase]]
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[[Category: Uhlin, U.]]
[[Category: Uhlin, U.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
 
[[Category: Deoxyribonucleoside kinase]]
[[Category: Deoxyribonucleoside kinase]]
[[Category: Dna synthesis]]
[[Category: Dna synthesis]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Zinc-binding domain]]
[[Category: Zinc-binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 13:44:16 2009''
 

Revision as of 18:16, 2 May 2012

Template:STRUCTURE 2wvj

Contents

Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine

Template:ABSTRACT PUBMED 22385435

About this Structure

2wvj is a 8 chain structure of Thymidine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Skovgaard T, Uhlin U, Munch-Petersen B. Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1. FEBS J. 2012 May;279(10):1777-87. doi: 10.1111/j.1742-4658.2012.08554.x. Epub, 2012 Mar 21. PMID:22385435 doi:10.1111/j.1742-4658.2012.08554.x

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