2wvj
From Proteopedia
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{{STRUCTURE_2wvj| PDB=2wvj | SCENE= }} | {{STRUCTURE_2wvj| PDB=2wvj | SCENE= }} | ||
- | === | + | ===Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine=== |
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==About this Structure== | ==About this Structure== | ||
- | + | [[2wvj]] is a 8 chain structure of [[Thymidine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVJ OCA]. | |
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+ | ==See Also== | ||
+ | *[[Thymidine kinase|Thymidine kinase]] | ||
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+ | ==Reference== | ||
+ | <ref group="xtra">PMID:022385435</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thymidine kinase]] | [[Category: Thymidine kinase]] | ||
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[[Category: Uhlin, U.]] | [[Category: Uhlin, U.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Deoxyribonucleoside kinase]] | [[Category: Deoxyribonucleoside kinase]] | ||
[[Category: Dna synthesis]] | [[Category: Dna synthesis]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Zinc-binding domain]] | [[Category: Zinc-binding domain]] | ||
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Revision as of 18:16, 2 May 2012
Contents |
Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine
Template:ABSTRACT PUBMED 22385435
About this Structure
2wvj is a 8 chain structure of Thymidine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Skovgaard T, Uhlin U, Munch-Petersen B. Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1. FEBS J. 2012 May;279(10):1777-87. doi: 10.1111/j.1742-4658.2012.08554.x. Epub, 2012 Mar 21. PMID:22385435 doi:10.1111/j.1742-4658.2012.08554.x