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1uxd

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(New page: 200px<br /> <applet load="1uxd" size="450" color="white" frame="true" align="right" spinBox="true" caption="1uxd" /> '''FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR,...)
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==About this Structure==
==About this Structure==
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1UXD is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UXD OCA]].
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1UXD is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Structure known Active Site: HTH. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UXD OCA]].
==Reference==
==Reference==
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[[Category: transcription regulation]]
[[Category: transcription regulation]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 20:19:00 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:13:04 2007''

Revision as of 11:08, 30 October 2007


1uxd

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FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, 34 STRUCTURES

Overview

FruR is an Escherichia coli transcriptional regulator that belongs to the, LacI DNA-binding protein family. By using 1H and 15N NMR spectroscopy, we, have determined the three-dimensional solution structure of the FruR, N-terminal DNA-binding domain consisting of 57 amino acid residues. A, total of 809 NMR-derived distances and 54 dihedral angle constraints have, been used for molecular modelling with the X-PLOR program. The resulting, set of calculated structures presents an average root-mean-square, deviation of 0.37 A at the main-chain level for the first 47 residues., This highly defined N-terminal part of the structure reveals a similar, topology for the three alpha-helices when compared to the 3D structures of, LacI and PurR counterparts. The most striking difference lies in the, ... [(full description)]

About this Structure

1UXD is a [Single protein] structure of sequence from [Escherichia coli]. Structure known Active Site: HTH. Full crystallographic information is available from [OCA].

Reference

Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR., Penin F, Geourjon C, Montserret R, Bockmann A, Lesage A, Yang YS, Bonod-Bidaud C, Cortay JC, Negre D, Cozzone AJ, Deleage G, J Mol Biol. 1997 Jul 18;270(3):496-510. PMID:9237914

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