Carbon monoxide dehydrogenase
From Proteopedia
Michal Harel (Talk | contribs)
(New page: <!-- Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page. Or use the four-green-boxes-button to insert scrollable text adjacent to a Jmol applet. Che...)
Next diff →
Revision as of 11:09, 3 May 2012
Carbon monoxide dehydrogenase (CODH) catalyzes the reversible conversion of CO to CO2. Two classes of CODH were identified: CODH containing 2Fe-Mo-2S-FAD cluster and CODH containing Fe3-Ni-S4 cluster. CODH can exist as a monofunctional enzyme and as a bifunctional enzyme with acetyl-CoA synthase (ACS) (see Acetyl-CoA synthase.
3D structures of carbon monoxide dehydrogenase
CODH monofunctional
1ffu – HpCODH + Fe2S2 + FAD – Hydrogenophaga pseudoflava
1ffv - HpCODH + Fe2S2 + molybdenum cofactor + FAD
1jqk - CODH + Fe4S4 + Fe + Fe3-Ni-S4 – Rhodospirillum rubrum
1n60 - OcCODH + Fe2S2 + H2MoO3 + pterin cytosine dinucleotide + FAD – Oligotropha carboxidovorans
1n61, 1n62, 1n63, 1n5w, 1zxi - OcCODH + Fe2S2 + Cu-Mo cluster + pterin cytosine dinucleotide + FAD
1su6, 1su7, 1su8, 1suf - ChCODH + Fe4S4 + Fe2S2 + Fe4-Ni-S5 – Carboxydothermus hydrogenoformans
3b51, 3b53 - ChCODH + Fe4S4 + Fe2S2 + Fe + Fe3-Ni
3b52 - ChCODH + Fe4S4 + Fe2S2 + Fe + CO2 + Fe3-Ni-S4
3i39 - ChCODH (mutant) + Fe4S4 + Fe2S2 + Fe + CN + Fe3-Ni-S4
2yiv - ChCODH (mutant) + Fe4S4 + Fe2S2 + Fe + butyl-isocyanide + Fe3-Ni-S4
CODH/ACS bifunctional
1mjg, 1oao, 2z8y, 3i01 – MtCODH/ACS α+β + Fe4-Ni-S4 – Moorella thermoacetica
3i04 - MtCODH/ACS α+β + CN + Fe4-Ni-S4
3git - MtCODH/ACS α + Fe4S4
3s2x - MtCODH/ACS α C terminal + Ni
2h9a - ChCODH/ACS γ + Fe4S4
2ycl - ChCODH/ACS γ + Fe4S4 + cobalamin
