4e4x
From Proteopedia
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| - | + | [[Image:4e4x.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_4e4x", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_4e4x| PDB=4e4x | SCENE= }} | ||
| - | + | ===Crystal Structure of B-Raf Kinase Domain in Complex with a Dihydropyrido[2,3-d]pyrimidinone-based Inhibitor=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22534450}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22534450 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22534450}} | ||
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| + | ==About this Structure== | ||
| + | [[4e4x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E4X OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022534450</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Sturgis, H L.]] | ||
| + | [[Category: Voegtli, W C.]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 09:08, 9 May 2012
Crystal Structure of B-Raf Kinase Domain in Complex with a Dihydropyrido[2,3-d]pyrimidinone-based Inhibitor
Template:ABSTRACT PUBMED 22534450
About this Structure
4e4x is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ren L, Ahrendt KA, Grina J, Laird ER, Buckmelter AJ, Hansen JD, Newhouse B, Moreno D, Wenglowsky S, Dinkel V, Gloor SL, Hastings G, Rana S, Rasor K, Risom T, Sturgis HL, Voegtli WC, Mathieu S. The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-Raf(V600E) kinase. Bioorg Med Chem Lett. 2012 May 15;22(10):3387-91. Epub 2012 Apr 10. PMID:22534450 doi:10.1016/j.bmcl.2012.04.015
