4dl4

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-	'''Unreleased structure'''	+	[[Image:4dl4.jpg|left|200px]]
-	The entry 4dl4 is ON HOLD until Paper Publication	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4dl4", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
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		+	{{STRUCTURE_4dl4| PDB=4dl4 | SCENE= }}
-	Authors: Zhao, Ye, Biertumpfel, Christian, Gregory, Mark, Hua, Yue-Jin, Hanaoka, Fumio, Yang, Wei	+	===Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).===
-	Description: Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22529383}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22529383 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22529383}}
		+
		+	==About this Structure==
		+	[[4dl4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL4 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022529383</ref><references group="xtra"/>
		+	[[Category: DNA-directed DNA polymerase]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Biertumpfel, Christian]]
		+	[[Category: Gregory, Mark]]
		+	[[Category: Hanaoka, Fumio]]
		+	[[Category: Hua, Yue-Jin]]
		+	[[Category: Yang, Wei]]
		+	[[Category: Zhao, Ye]]
		+	[[Category: Chemoresistence]]
		+	[[Category: Cisplatin]]
		+	[[Category: Dna distorsion]]
		+	[[Category: Human dna polymerse eta]]
		+	[[Category: Inhibition]]
		+	[[Category: Kinetic]]
		+	[[Category: Molecular splint]]
		+	[[Category: Nucleotidyl transfer reaction]]
		+	[[Category: Pcna]]
		+	[[Category: Second tls polymerase]]
		+	[[Category: Transferase-dna-inhibitor complex]]
		+	[[Category: Translesion synthesis]]

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Revision as of 09:09, 9 May 2012

Template:STRUCTURE 4dl4

Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).

Template:ABSTRACT PUBMED 22529383

About this Structure

4dl4 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109