3v04

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'''Unreleased structure'''
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[[Image:3v04.jpg|left|200px]]
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The entry 3v04 is ON HOLD until Paper Publication
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{{STRUCTURE_3v04| PDB=3v04 | SCENE= }}
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Authors: Heald, R., Jackson, P., Savy, P., Jones, M., Gancia, E., Burton, B., Newman, R., Boggs, J., Chan, E., Chan, J., Choo, E., Merchant, M., Ultsch, M., Wiesmann, C., Belvin, M., Price, S.
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===Discovery of Novel Allosteric MEK Inhibitors Possessing Classical and Non-classical Bidentate Ser212 Interactions.===
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Description: Discovery of Novel Allosteric MEK Inhibitors Possessing Classical and Non-classical Bidentate Ser212 Interactions.
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{{ABSTRACT_PUBMED_22506516}}
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==About this Structure==
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[[3v04]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V04 OCA].
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==Reference==
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<ref group="xtra">PMID:022506516</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Mitogen-activated protein kinase kinase]]
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[[Category: Belvin, M.]]
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[[Category: Boggs, J.]]
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[[Category: Burton, B.]]
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[[Category: Chan, E.]]
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[[Category: Chan, J.]]
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[[Category: Choo, E.]]
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[[Category: Gancia, E.]]
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[[Category: Heald, R.]]
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[[Category: Jackson, P.]]
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[[Category: Jones, M.]]
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[[Category: Merchant, M.]]
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[[Category: Newman, R.]]
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[[Category: Price, S.]]
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[[Category: Savy, P.]]
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[[Category: Ultsch, M.]]
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[[Category: Wiesmann, C.]]
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[[Category: Kinase]]
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[[Category: Transferase-inhibitor complex]]

Revision as of 09:12, 9 May 2012

Image:3v04.jpg

Template:STRUCTURE 3v04

Discovery of Novel Allosteric MEK Inhibitors Possessing Classical and Non-classical Bidentate Ser212 Interactions.

Template:ABSTRACT PUBMED 22506516

About this Structure

3v04 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Heald RA, Jackson P, Savy P, Jones M, Gancia E, Burton B, Newman R, Boggs J, Chan E, Chan J, Choo E, Merchant M, Rudewicz P, Ultsch M, Wiesmann C, Yue Q, Belvin M, Price S. Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions. J Med Chem. 2012 May 3. PMID:22506516 doi:10.1021/jm2017094

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OCA

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