2ipj
From Proteopedia
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[[Image:2ipj.png|left|200px]] | [[Image:2ipj.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_17442338}} | {{ABSTRACT_PUBMED_17442338}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Obesity, hyperphagia, and developmental delay OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600450 600450]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2ipj]] is a 2 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPJ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017442338</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Breton, R.]] | [[Category: Breton, R.]] | ||
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[[Category: Open conformation]] | [[Category: Open conformation]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 10:34:49 2009'' | ||
Revision as of 08:25, 16 May 2012
Contents |
Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant Y24A in complex with NADP+ and epi-testosterone
Template:ABSTRACT PUBMED 17442338
About this Structure
2ipj is a 2 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Faucher F, Cantin L, Pereira de Jesus-Tran K, Lemieux M, Luu-The V, Labrie F, Breton R. Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding. J Mol Biol. 2007 Jun 1;369(2):525-40. Epub 2007 Mar 27. PMID:17442338 doi:10.1016/j.jmb.2007.03.058
