4drk

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'''Unreleased structure'''
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[[Image:4drk.jpg|left|200px]]
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The entry 4drk is ON HOLD until Paper Publication
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{{STRUCTURE_4drk| PDB=4drk | SCENE= }}
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Authors: Gopalakrishnan, R., Kozany, C., Gaali, S., Kress, C., Hoogeland, B., Bracher, A., Hausch, F.
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===EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid===
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Description: EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
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{{ABSTRACT_PUBMED_22455444}}
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==About this Structure==
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[[4drk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRK OCA].
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==Reference==
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<ref group="xtra">PMID:022455444</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Bracher, A.]]
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[[Category: Gaali, S.]]
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[[Category: Gopalakrishnan, R.]]
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[[Category: Hausch, F.]]
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[[Category: Hoogeland, B.]]
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[[Category: Kozany, C.]]
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[[Category: Kress, C.]]
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[[Category: Fk-506 binding domain]]
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[[Category: Hsp90 cochaperone]]
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[[Category: Immunophilin]]
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[[Category: Isomerase]]
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[[Category: Peptidyl-prolyl isomerase]]

Revision as of 09:14, 16 May 2012

Image:4drk.jpg

Template:STRUCTURE 4drk

EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid

Template:ABSTRACT PUBMED 22455444

About this Structure

4drk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gopalakrishnan R, Kozany C, Gaali S, Kress C, Hoogeland B, Bracher A, Hausch F. Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52. J Med Chem. 2012 May 10;55(9):4114-22. Epub 2012 Apr 19. PMID:22455444 doi:10.1021/jm201746x

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OCA

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