4a7c

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Revision as of 04:59, 23 May 2012

Image:4a7c.png

Template:STRUCTURE 4a7c

Crystal structure of PIM1 kinase with ETP46546

Template:ABSTRACT PUBMED 22266039

About this Structure

4a7c is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pastor J, Oyarzabal J, Saluste G, Alvarez RM, Rivero V, Ramos F, Cendon E, Blanco-Aparicio C, Ajenjo N, Cebria A, Albarran MI, Cebrian D, Corrionero A, Fominaya J, Montoya G, Mazzorana M. Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1591-7. Epub 2012 Jan 5. PMID:22266039 doi:10.1016/j.bmcl.2011.12.130

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OCA

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